Cocaine induces apoptosis in primary cultured rat aortic vascular smooth muscle cells: possible relationship to aortic dissection, atherosclerosis, and hypertension.

@article{Su2004CocaineIA,
  title={Cocaine induces apoptosis in primary cultured rat aortic vascular smooth muscle cells: possible relationship to aortic dissection, atherosclerosis, and hypertension.},
  author={Jialin Su and Jianfeng Li and Wenyan Li and Bella T. Altura and Burton M. Altura},
  journal={International journal of toxicology},
  year={2004},
  volume={23 4},
  pages={233-7}
}
Cocaine abuse is known to induce many adverse cardiovascular effects, including hypertension, atherosclerosis, and aortic dissection. A major physiological event leading to these pathophysiological actions of cocaine could be apoptosis. This study was designed to investigate if primary cultured rat aortic vascular smooth muscle cells (VSMCs) can undergo… CONTINUE READING