Cocaine dysregulates opioid gating of GABA neurotransmission in the ventral pallidum.

Abstract

The ventral pallidum (VP) is a target of dense nucleus accumbens projections. Many of these projections coexpress GABA and the neuropeptide enkephalin, a δ and μ opioid receptor (MOR) ligand. Of these two, the MOR in the VP is known to be involved in reward-related behaviors, such as hedonic responses to palatable food, alcohol intake, and reinstatement of… (More)
DOI: 10.1523/JNEUROSCI.4336-13.2014

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