Cocaine and the AP‐1 Transcription Factor Complex

@article{Hope1998CocaineAT,
  title={Cocaine and the AP‐1 Transcription Factor Complex},
  author={Bruce T. Hope},
  journal={Annals of the New York Academy of Sciences},
  year={1998},
  volume={844}
}
  • B. Hope
  • Published 1 May 1998
  • Biology
  • Annals of the New York Academy of Sciences
ABSTRACT: Cocaine addiction in humans develops gradually with repeated administrations and persists long after cocaine has cleared the body. The mechanisms underlying this persistent form of neuroplasticity are not understood and can involve both structural and biochemical mechanisms. The long time course for cocaine addiction in humans and for development of cocaine self‐administration in animal models suggests the involvement of alterations in gene expression leading to altered signaling in… 
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