Cocaine abusers have reduced auditory P50 amplitude and suppression compared to both normal controls and alcoholics.

@article{Fein1996CocaineAH,
  title={Cocaine abusers have reduced auditory P50 amplitude and suppression compared to both normal controls and alcoholics.},
  author={George Fein and Christie Biggins and S R Mackay},
  journal={Biological psychiatry},
  year={1996},
  volume={39 11},
  pages={955-65}
}
The auditory P50 evoked response to click stimuli was recorded from 10 2-week abstinent African-American chronic cocaine abusers and 10 African-American non-substance-abusing controls. Stimuli consisted of pairs of clicks with a 500-msec interval between clicks in a pair, and a 7-8 sec interval between pairs of clicks. After averaging responses to 100 pairs of clicks and digital bandpass filtering between 10 and 50 Hz, P50 amplitude to the first and the second click was measured. The… CONTINUE READING

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