Cocaine Self-Administration Produces Long-Lasting Alterations in Dopamine Transporter Responses to Cocaine.

@article{Siciliano2016CocaineSP,
  title={Cocaine Self-Administration Produces Long-Lasting Alterations in Dopamine Transporter Responses to Cocaine.},
  author={Cody A Siciliano and Steve C Fordahl and Sara R Jones},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2016},
  volume={36 30},
  pages={7807-16}
}
UNLABELLED Cocaine addiction is a debilitating neuropsychiatric disorder characterized by uncontrolled cocaine intake, which is thought to be driven, at least in part, by cocaine-induced deficits in dopamine system function. A decreased ability of cocaine to elevate dopamine levels has been repeatedly observed as a consequence of cocaine use in humans, and preclinical work has highlighted tolerance to cocaine's effects as a primary determinant in the development of aberrant cocaine taking… CONTINUE READING
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