Cocaine-Associated Stimuli Increase Cocaine Seeking and Activate Accumbens Core Neurons after Abstinence

@article{Hollander2007CocaineAssociatedSI,
  title={Cocaine-Associated Stimuli Increase Cocaine Seeking and Activate Accumbens Core Neurons after Abstinence},
  author={Jonathan A. Hollander and R. Carelli},
  journal={The Journal of Neuroscience},
  year={2007},
  volume={27},
  pages={3535 - 3539}
}
  • Jonathan A. Hollander, R. Carelli
  • Published 2007
  • Psychology, Medicine
  • The Journal of Neuroscience
  • Electrophysiological recordings were completed in rats (n = 14) trained to self-administer cocaine to determine whether activation of nucleus accumbens (Acb) neurons (core vs shell) by cocaine-associated stimuli is enhanced after 1 month of cocaine abstinence. After self-administration training, 170 cells were recorded during a single test session conducted either the next day or 1 month later. The test session consisted of three phases during which (1) the cocaine cue was presented… CONTINUE READING
    137 Citations

    Figures and Topics from this paper

    Prelimbic and infralimbic cortical regions differentially encode cocaine‐associated stimuli and cocaine‐seeking before and following abstinence
    • 43
    Incubation of Cocaine Seeking following Brief Cocaine Experience in Mice Is Enhanced by mGluR1 Blockade
    • 21
    • PDF

    References

    SHOWING 1-10 OF 33 REFERENCES
    Abstinence from Cocaine Self-Administration Heightens Neural Encoding of Goal-Directed Behaviors in the Accumbens
    • 81
    • PDF
    Activation of accumbens cell firing by stimuli associated with cocaine delivery during self‐administration
    • 70
    Persistent Cue-Evoked Activity of Accumbens Neurons after Prolonged Abstinence from Self-Administered Cocaine
    • 130
    • Highly Influential
    • PDF
    Fos Protein Expression and Cocaine-Seeking Behavior in Rats after Exposure to a Cocaine Self-Administration Environment
    • 406
    • Highly Influential
    • PDF
    Differential control over cocaine-seeking behavior by nucleus accumbens core and shell
    • 440
    • PDF
    Enduring Resistance to Extinction of Cocaine-Seeking Behavior Induced by Drug-Related Cues
    • 174
    • PDF
    Neuronal substrates of relapse to cocaine-seeking behavior: role of prefrontal cortex.
    • G. Rebec, W. Sun
    • Psychology, Medicine
    • Journal of the experimental analysis of behavior
    • 2005
    • 73
    • PDF