Cocaine, but not morphine, induces conditioned place preference and sensitization to locomotor responses in CB1 knockout mice.

@article{Martn2000CocaineBN,
  title={Cocaine, but not morphine, induces conditioned place preference and sensitization to locomotor responses in CB1 knockout mice.},
  author={Margarita Mart{\'i}n and Catherine A. Ledent and Marc Parmentier and Rafael Gonz{\'a}lez Maldonado and Olga Valverde},
  journal={The European journal of neuroscience},
  year={2000},
  volume={12 11},
  pages={
          4038-46
        }
}
The involvement of cannabinoid CB1 receptors in morphine and cocaine motivational effects was investigated using CB1 knockout mice. For this purpose, we evaluated the rewarding effects in the place conditioning paradigm and the sensitization to the locomotor responses induced by these drugs. The hyperlocomotion induced by acute morphine administration (15 mg/kg, s.c.) was preserved, but the sensitization to this locomotor response induced by chronic morphine treatment was abolished in CB1… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 108 CITATIONS

FILTER CITATIONS BY YEAR

2001
2019

CITATION STATISTICS

  • 14 Highly Influenced Citations

  • Averaged 6 Citations per year over the last 3 years

Similar Papers

Loading similar papers…