Cobalt-catalyzed cycloisomerization of 1,6-enynes and allyl propargyl ethers.

@article{Ajamian2003CobaltcatalyzedCO,
  title={Cobalt-catalyzed cycloisomerization of 1,6-enynes and allyl propargyl ethers.},
  author={Alain Ajamian and James L. Gleason},
  journal={Organic letters},
  year={2003},
  volume={5 14},
  pages={2409-11}
}
[reaction: see text] 1,6-Enynes and allyl propargyl ethers undergo a cobalt-catalyzed formal 5-endo-dig cyclization to form vinyl cyclopentenes and dihydrofurans, respectively. The use of equimolar amounts of dicobalt octacarbonyl and trimethyl phosphite affords optimum yields and improved selectivity for cycloisomerization vs alkene isomerization.