Cobalt Chloride-induced Hypoxia Induces Epithelial-mesenchymal Transition in Renal Carcinoma Cell Lines.

Abstract

OBJECTIVE To establish epithelial-mesenchymal transition (EMT) models in renal cell carcinoma (RCC) cell lines. MATERIALS AND METHODS The RCC cell lines A498 and 786-O were used in the experiment and CoCl2 was used to simulate hypoxia. Cells were cultured with different concentrations of CoCl2. Morphology and changes in cytoactivity were observed. After… (More)

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@article{Zhang2017CobaltCH, title={Cobalt Chloride-induced Hypoxia Induces Epithelial-mesenchymal Transition in Renal Carcinoma Cell Lines.}, author={Ning Zhang and Baoan Hong and Changhua Zhou and Xin Du and Siqi Chen and Xiaohu Deng and Shayiremu Duoerkun and Qing Li and Yong Yang and Kan Gong}, journal={Annals of clinical and laboratory science}, year={2017}, volume={47 1}, pages={40-46} }