Cobalt, chromium and nickel affect hydroxyapatite crystal growth in vitro.

  title={Cobalt, chromium and nickel affect hydroxyapatite crystal growth in vitro.},
  author={Guillaume Mabilleau and Robert Filmon and Peter K Petrov and Michel F{\'e}lix Basl{\'e} and Afsie Sabokbar and Daniel Chappard},
  journal={Acta biomaterialia},
  volume={6 4},
Metals are widely used in orthopaedics and recent studies have reported that patients with metal implants have a significant increase of metal levels in serum and synovial fluid. Femoral neck fracture occurred in some patients with metal-on-metal implants for unknown reasons. Recently, bone quality has emerged as an important factor of bone strength and few studies have investigated the effects of metal ions on hydroxyapatite properties. In the present study, we investigated the effects of Co(2… CONTINUE READING


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