Cobalt(II)/ N-Hydroxyphthalimide-Catalyzed Cross-Dehydrogenative Coupling Reaction at Room Temperature under Aerobic Condition.

@article{Patil2018CobaltIINC,
  title={Cobalt(II)/ N-Hydroxyphthalimide-Catalyzed Cross-Dehydrogenative Coupling Reaction at Room Temperature under Aerobic Condition.},
  author={Mahendra R Patil and Noopur P Dedhia and Anant R Kapdi and A Vijay Kumar},
  journal={The Journal of organic chemistry},
  year={2018},
  volume={83 8},
  pages={
          4477-4490
        }
}
This work reports a cobalt(II)/ N-hydroxyphthalimide (NHPI)-catalyzed cross-dehydrogenative oxidative coupling of N-aryl tetrahydroisoquinolines with various pro-nucleophiles, such as indoles, nitroalkanes, and trialkylphosphites, active methylene compounds, and other nucleophiles, such as cyanide (ethyl cyanoformate), at room temperature under aerobic… CONTINUE READING