Coating lanthanide nanoparticles with carbohydrate ligands elicits affinity for HeLa and RAW264.7 cells, enhancing their photodamaging effect.

@article{Kanamori2017CoatingLN,
  title={Coating lanthanide nanoparticles with carbohydrate ligands elicits affinity for HeLa and RAW264.7 cells, enhancing their photodamaging effect.},
  author={Takashi Kanamori and Takashi Sawamura and Tatsumi Tanaka and Izumi Sotokawa and Ryota Mori and Kotaro Inada and Akihiro Ohkubo and Shun-ichiro Ogura and Yasutoshi Murayama and Eigo Otsuji and Hideya Yuasa},
  journal={Bioorganic & medicinal chemistry},
  year={2017},
  volume={25 2},
  pages={743-749}
}
Lanthanide nanoparticles (LNPs) conjugated with monosaccharides were synthesized as a photon energy-upconverting nanodevice with affinity to cancer cells. The conjugates were designed to selectively damage the cancer cells containing protoporphyrin IX, a photosensitizer endogenously synthesized from priorly administrated 5-aminolevlunic acid (ALA), by a… CONTINUE READING