Coagulopathy and platelet activation in Kawasaki syndrome: identification of patients at high risk for development of coronary artery aneurysms.

@article{Burns1984CoagulopathyAP,
  title={Coagulopathy and platelet activation in Kawasaki syndrome: identification of patients at high risk for development of coronary artery aneurysms.},
  author={Jane C. Burns and Mary P. Glod{\'e} and Stephen H. Clarke and J Mark Wiggins and William E Hathaway},
  journal={The Journal of pediatrics},
  year={1984},
  volume={105 2},
  pages={
          206-11
        }
}
Prospective evaluation of platelet activation and hypercoagulability was performed in 31 patients with Kawasaki syndrome. Most patients had elevated acute-phase reactants when studied during the first 3 weeks of their illness; 17 of 25 (68%) patients had factor VIII activity greater than 150%, 18 of 24 (75%) had fibrinogen greater than 400 mg/dl, and 17 of 31 (55%) had a platelet count greater than 450,000/mm3. Antithrombin III was depressed initially in 17 of 25 (68%) patients. Depleted… CONTINUE READING