Coagulopathy After Cardiopulmonary Bypass in Jehovah’s Witness Patients: Management of Two Cases Using Fractionated Components and Factor VIIa

@article{Sniecinski2007CoagulopathyAC,
  title={Coagulopathy After Cardiopulmonary Bypass in Jehovah’s Witness Patients: Management of Two Cases Using Fractionated Components and Factor VIIa},
  author={Roman M. Sniecinski and Edward P. Chen and Jerrold H. Levy and Fania Szlam and Kenichi A. Tanaka},
  journal={Anesthesia \& Analgesia},
  year={2007},
  volume={104},
  pages={763-765}
}
BACKGROUND:Changes in the Jehovah's Witness (JW) blood refusal policy now give members the personal choice to accept certain processed fractions of blood, such as factor concentrates and cryoprecipitate. METHODS:Two JW patients undergoing complex aortic surgery who developed severe microvascular bleeding after prolonged use of cardiopulmonary bypass were treated with recombinant activated factor VII, cryoprecipitate, and antithrombin concentrate. RESULTS:Cardiopulmonary bypass-induced… 

Coagulopathy after cardiopulmonary bypass in Jehovah's Witness patients: management of and for the individual rather than the religious institution.

  • Lee Elder
  • Medicine
    Anesthesia and analgesia
  • 2007
TLDR
Lee Elder Jehovah’s Witnesses read with interest the case study by Sniecinski et al. (1) concerning advances in treating patients who refuse certain products made from blood, and is grateful to medical science for advances facilitating safe perioperative care for patients with this preference.

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It is thought that a patient's status as a Jehovah's Witness need not preclude potentially life-saving cardiac operations, and the repair of a large pulmonary artery aneurysm in a 71-year-old woman who was a Jehovah’s Witness is reported.

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  • M. Ragni
  • Medicine, Biology
    Hematology. American Society of Hematology. Education Program
  • 2013
TLDR
Understanding the comparative coagulation studies of established prohemostatic agents, the pharmacokinetics of new long-acting clotting factors, and their correlation with bleeding outcomes will provide opportunities to optimize the hemostatic management of both congenital and acquired he mostatic disorders.

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