• Corpus ID: 11803214

Coagulation profile in diabetes and its association with diabetic microvascular complications.

@article{Madan2010CoagulationPI,
  title={Coagulation profile in diabetes and its association with diabetic microvascular complications.},
  author={Ritu Madan and Bhuvanesh Gupt and Sumita Saluja and Uc Kansra and B K Tripathi and Brahm Prakash Guliani},
  journal={The Journal of the Association of Physicians of India},
  year={2010},
  volume={58},
  pages={
          481-4
        }
}
OBJECTIVES To investigate the haemostatic parameters and to assesss their relationship with microvascular complications in type 2 diabetes mellitus. MATERIALS AND METHODS Coagulation and fibrinolysis parameters were measured in 60 type 2 diabetic patients (M:F 1:1) with (n=40) and without (n=20) diabetic microvascular complications and in 30 nondiabetic healthy subjects (M:F 1:1). RESULTS The mean age of diabetic patients and healthy controls was 56.9 +/- 8.78 and 53.2 +/- 7.58 respectively… 
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78 Citations
Highly Influential Citations
5
Background Citations
27
Results Citations
2

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78 Citations

Clinical Significance of Hemostatic Parameters in the Prediction for Type 2 Diabetes Mellitus and Diabetic Nephropathy
TLDR
It is suggested that hemostatic parameters have a low predicting value for T2DM, whereas fibrinogen is a powerful predictor for DN.
Correlation of Fibrinogen and HsCRP with Microvascular Complications of Type 2 Diabetes Mellitus.
TLDR
Fibrinogen contributes to procoagulant state observed in diabetes, which leads to vascular complications and microvascular complications of diabetes, and microalbuminuria is the best predictor of fibr inogen levels in T2DM.
Coagulation factors IX and XI activities are significantly enhanced in type 2 diabetic patients
TLDR
Procoagulant state in DM2 as evidenced by enhanced activation of coagulation factors IX and XI and elevated fibrinogen concentration, may contribute to the increased risk of thrombosis and vascular complications inDM2 patients.
EFFECT OF DIABETES MELLITUS TYPE II ON ACTIVATED PARTIAL THROMBOPLASTIN
TLDR
It may be concluded that shorted APTT confirms that T2DM is a hyper-coagulable state due to which there is increased risk of thrombotic events.
Association of coagulation profile with microvascular complications and glycemic control in type 2 diabetes mellitus – a study at a tertiary care center in Delhi
COMPARISON OF PROTHROMBIN TIME AND ACTIVATED PARTIAL THROMBOPLASTIN TIME BETWEEN PATIENTS WITH DIABETES MELLITUS AND DIABETICS WITH HYPERTENSION
TLDR
This study showed Prolonged PT and APTT in diabetes mellitus with hypertension, which are the indications of altered activity or absence or decreased levels of clotting factors of intrinsic & extrinsic coagulation pathways respectively.
Inflammation, Haemostatic Disturbance, and Obesity: Possible Link to Pathogenesis of Diabetic Retinopathy in Type 2 Diabetes
TLDR
Logistic regression analyses showed that diabetes duration and prolonged poor glycemic control are the main predictors of retinopathy in patients with type 2 diabetes.
Serum fibrinogen level in type 2 diabetes mellitus patients
TLDR
The serum fibrinogen level in patients of Type 2 diabetes and correlate it with parameters like glycemic control (HbA1C), duration of diabetes mellitus, complications and pharmacotherapy is estimated to be higher in overweight patients as compared to normal weight patient in all groups.
Serum high sensitivity C-reactive protein, nitric oxide metabolites, plasma fibrinogen, and lipid parameters in Indian type 2 diabetic males.
Hemostatic state of children with type 1 diabetes
TLDR
Elevated levels of fibrinogen, PAI-1, and von Willebrand factor antigen were found in the pediatric and adolescent population with type 1 diabetes mellitus, which suggests a prothrombotic state.
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