Coagulation inhibitors in inflammation.

@article{Esmon2005CoagulationII,
  title={Coagulation inhibitors in inflammation.},
  author={Charles T. Esmon},
  journal={Biochemical Society transactions},
  year={2005},
  volume={33 Pt 2},
  pages={
          401-5
        }
}
Coagulation is triggered by inflammatory mediators in a number of ways. However, to prevent unwanted clot formation, several natural anticoagulant mechanisms exist, such as the antithrombin-heparin mechanism, the tissue factor pathway inhibitor mechanism and the protein C anticoagulant pathway. This review examines the ways in which these pathways are down-regulated by inflammation, thus limiting clot formation and decreasing the natural anti-inflammatory mechanisms that these pathways possess. 

Figures and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 23 CITATIONS