Coagulation abnormalities in Legg-Calvé-Perthes disease.

  title={Coagulation abnormalities in Legg-Calv{\'e}-Perthes disease.},
  author={Alexander Vosmaer and Rob Rodrigues Pereira and Jorine S. Koenderman and Frits R Rosendaal and Suzanne C Cannegieter},
  journal={The Journal of bone and joint surgery. American volume},
  volume={92 1},
BACKGROUND Legg-Calvé-Perthes disease is a pediatric disorder characterized by osteonecrosis of the proximal femoral epiphysis. The etiology probably involves successive vascular occlusions, in which hypercoagulable disorders may play a role. We evaluated the etiologic role of thrombophilia in Legg-Calvé-Perthes disease in a pediatric population. METHODS One hundred and sixty-nine consecutive patients who had been diagnosed with Legg-Calvé-Perthes disease at two centers in Rotterdam, the… CONTINUE READING
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