Coadministration of atropine, NBQX and TCP against soman-induced seizures.

@article{Lallement1994CoadministrationOA,
  title={Coadministration of atropine, NBQX and TCP against soman-induced seizures.},
  author={Guy Lallement and Irmine Pernot-Marino and A Foquin-Tarricone and Dominique Baubichon and Antonio Piras and G{\'e}rard Blanchet and Pierre Carpentier},
  journal={Neuroreport},
  year={1994},
  volume={5 9},
  pages={
          1113-7
        }
}
The ability of relatively low doses of atropine, NBQX and TCP administered in combination to prevent or stop seizures induced by soman, was studied in rats. While these drugs injected together early after soman prevented the onset of seizures, their delayed concomitant administration after 5 or 30 min of epileptic activity only mildly attenuated the intensity of seizures. Conversely, a total arrest of epileptic activity was observed in 80 to 100% of animals when NBQX and TCP were given together… CONTINUE READING

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