CoNCoS: Copy number estimation in cancer with controlled support

Abstract

Somatic copy number (CN) alterations are major drivers of tumorigenesis and growth. Although next-generation sequencing (NGS) technologies enable a deep genomic analysis of cancers, the analysis of the data remains subject to biases and multiple sources of error, including varying local read coverage. The currently existing algorithms for NGS-based… (More)
DOI: 10.1142/S0219720015500274

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Cite this paper

@article{Abdallah2015CoNCoSCN, title={CoNCoS: Copy number estimation in cancer with controlled support}, author={Ali T. Abdallah and Matthias Fischer and Peter N{\"{u}rnberg and Michael Nothnagel and Peter Frommolt}, journal={Journal of bioinformatics and computational biology}, year={2015}, volume={13 5}, pages={1550027} }