CoMoDis: composite motif discovery in mammalian genomes

  title={CoMoDis: composite motif discovery in mammalian genomes},
  author={Ian John Donaldson and Berthold G{\"o}ttgens},
  booktitle={Nucleic acids research},
Specificity of mammalian gene regulatory regions is achieved to a large extent through the combinatorial binding of sets of transcription factors to distinct binding sites, discrete combinations of which are often referred to as regulatory modules. Identification and subsequent characterization of gene regulatory modules will be a key step in assembling transcriptional regulatory networks from gene expression profiling data, with the ultimate goal of unravelling the regulatory codes that govern… CONTINUE READING
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