Co-trimoxazole use restricted

  title={Co-trimoxazole use restricted},
  journal={Drug and Therapeutics Bulletin},
  pages={92 - 93}
  • Published 1995
  • Medicine
  • Drug and Therapeutics Bulletin
  • Co-trimoxazole, the fixed-dose preparation of trimethoprim (80mg) plus sulphamethoxazole (400mg), has been available in the UK since 1969. At its launch the Drug and Therapeutics Bulletin accepted the logic of using the combination1 but advised prescribers to be alert to the possibility of unwanted effects. In 1980 we advised that, in some infections, a single antibiotic might be at least as effective as co-trimoxazole, with a lower risk of unwanted effects.2 Later that year, when trimethoprim… CONTINUE READING
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