Co-translational protein targeting to the bacterial membrane.

@article{Saraogi2014CotranslationalPT,
  title={Co-translational protein targeting to the bacterial membrane.},
  author={Ishu Saraogi and Shu-Ou Shan},
  journal={Biochimica et biophysica acta},
  year={2014},
  volume={1843 8},
  pages={
          1433-41
        }
}
Co-translational protein targeting by the Signal Recognition Particle (SRP) is an essential cellular pathway that couples the synthesis of nascent proteins to their proper cellular localization. The bacterial SRP, which contains the minimal ribonucleoprotein core of this universally conserved targeting machine, has served as a paradigm for understanding the molecular basis of protein localization in all cells. In this review, we highlight recent biochemical and structural insights into the… CONTINUE READING
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