Co-transcription of the celC gene cluster in Clostridium thermocellum

@article{Newcomb2011CotranscriptionOT,
  title={Co-transcription of the celC gene cluster in Clostridium thermocellum},
  author={Michael N Newcomb and Jonathan K. Millen and Chun-Yu Chen and Junqing. Wu},
  journal={Applied Microbiology and Biotechnology},
  year={2011},
  volume={90},
  pages={625-634}
}
Clostridium thermocellum, an anaerobic, thermophilic, and ethanogenic bacterium produces a large cellulase complex termed the cellulosome and many free glycosyl hydrolases. Most cellulase genes scatter around the genome. We mapped the transcripts of the six-gene cluster celC–glyR3–licA–orf4–manB–celT and determined their transcription initiation sites by primer extension. Northern blot showed that celC–glyR3–licA were co-transcribed into a polycistronic messenger with the transcription… CONTINUE READING
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