Co-response analysis: a new experimental strategy for metabolic control analysis.

@article{Hofmeyr1996CoresponseAA,
  title={Co-response analysis: a new experimental strategy for metabolic control analysis.},
  author={Jan-Hendrik S. Hofmeyr and A. Cornish-Bowden},
  journal={Journal of theoretical biology},
  year={1996},
  volume={182 3},
  pages={371-80}
}
The formulation of the standard summation and connectivity relationships as a statement that the matrix of all the elasticities in a system is the inverse of the matrix of all the control coefficients is completely general, provided that only control coefficients for independent fluxes and concentrations are considered, and that the elasticity matrix is written to take account of the stoichiometry of the pathway and the implied dependences between concentrations. This generally implies that co… CONTINUE READING