Co-regulation of the Notch and Wnt signaling pathways promotes supporting cell proliferation and hair cell regeneration in mouse utricles

@inproceedings{Wu2016CoregulationOT,
  title={Co-regulation of the Notch and Wnt signaling pathways promotes supporting cell proliferation and hair cell regeneration in mouse utricles},
  author={Jingfang Wu and Wenyan Li and Chen Lin and Yan Chen and Cheng Cheng and Shan Sun and Mingliang Tang and Renjie Chai and Huawei Li},
  booktitle={Scientific reports},
  year={2016}
}
This work sought to determine the crosstalk between the Notch and Wnt signaling pathways in regulating supporting cell (SC) proliferation and hair cell (HC) regeneration in mouse utricles. We cultured postnatal day (P)3 and P60 mouse utricles, damaged the HCs with gentamicin, and treated the utricles with the γ-secretase inhibitor DAPT to inhibit the Notch… CONTINUE READING