Co-regulation of caveolar and Cdc42-dependent fluid phase endocytosis by phosphocaveolin-1.

  title={Co-regulation of caveolar and Cdc42-dependent fluid phase endocytosis by phosphocaveolin-1.},
  author={Zhi-jie Cheng and Raman Deep Singh and Eileen L. Holicky and Christine L. Wheatley and David L. Marks and Richard E. Pagano},
  journal={The Journal of biological chemistry},
  volume={285 20},
Several clathrin-independent endocytosis mechanisms have been identified that can be distinguished by specific requirements for certain proteins, such as caveolin-1 (Cav1) and the Rho GTPases, RhoA and Cdc42, as well as by specific cargo. Some endocytic pathways may be co-regulated such that disruption of one pathway leads to the up-regulation of another; however, the underlying mechanisms for this are unclear. Cav1 has been reported to function as a guanine nucleotide dissociation inhibitor… CONTINUE READING

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