Co-ordinated expression of MMP-2 and its putative activator, MT1-MMP, in human placentation.

@article{Bjrn1997CoordinatedEO,
  title={Co-ordinated expression of MMP-2 and its putative activator, MT1-MMP, in human placentation.},
  author={S. Frahm Bj\orn and Nina Hastrup and Leif R\oge Lund and Keld Dan\o and J\orgen Falck Larsen and Charles Pyke},
  journal={Molecular human reproduction},
  year={1997},
  volume={3 8},
  pages={713-23}
}
The spatial expression of mRNA for matrix metalloproteinase 2 (MMP-2), its putative activator, the membrane-type 1 matrix metalloproteinase (MT1-MMP), and the MMP-2 substrate type IV collagen was investigated in human placentas of both normal and tubal ectopic pregnancies and in cyclic endometrium using in-situ hybridization. Cytokeratin staining applied to adjacent sections was used to identify epithelial and trophoblast cells. In both normal and tubal pregnancies MT1-MMP, MMP-2 and type IV… CONTINUE READING
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