Co-ordinated autophagy with resveratrol and γ-tocotrienol confers synergetic cardioprotection

@inproceedings{Lekli2010CoordinatedAW,
  title={Co-ordinated autophagy with resveratrol and γ-tocotrienol confers synergetic cardioprotection},
  author={Istvan Lekli and Diptarka Ray and Subhendu Mukherjee and Narasimman Gurusamy and Md Kaimul Ahsan and B{\'e}la Juh{\'a}sz and Istv{\'a}n Bak and Arp{\'a}d T{\'o}saki and Mihaela Gherghiceanu and Lawrence M Popescu and Dipak Kumar Das},
  booktitle={Journal of cellular and molecular medicine},
  year={2010}
}
This study compared two dietary phytochemicals, grape-derived resveratrol and palm oil-derived γ-tocotrienol, either alone or in combination, on the contribution of autophagy in cardioprotection during ischaemia and reperfusion. Sprague-Dawley rats weighing between 250 and 300 g were randomly assigned to one of the following groups: vehicle, ischaemia/reperfusion (I/R), resveratrol + I/R, γ-tocotrienol + I/R, resveratrol +γ-tocotrienol + I/R. For resveratrol treatments, the rats were gavaged… CONTINUE READING