Co-occurrence of Local Anisotropic Gradient Orientations (CoLlAGe): A new radiomics descriptor

  title={Co-occurrence of Local Anisotropic Gradient Orientations (CoLlAGe): A new radiomics descriptor},
  author={Prateek Prasanna and Pallavi Tiwari and Anant Madabhushi},
  journal={Scientific Reports},
In this paper, we introduce a new radiomic descriptor, Co-occurrence of Local Anisotropic Gradient Orientations (CoLlAGe) for capturing subtle differences between benign and pathologic phenotypes which may be visually indistinguishable on routine anatomic imaging. CoLlAGe seeks to capture and exploit local anisotropic differences in voxel-level gradient orientations to distinguish similar appearing phenotypes. CoLlAGe involves assigning every image voxel an entropy value associated with the co… 

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