Co-localization of 5-HT(1B/1D/1F) receptors and glutamate in trigeminal ganglia in rats.

@article{Ma2001ColocalizationO5,
  title={Co-localization of 5-HT(1B/1D/1F) receptors and glutamate in trigeminal ganglia in rats.},
  author={Qing-ping Ma},
  journal={Neuroreport},
  year={2001},
  volume={12 8},
  pages={1589-91}
}
Anti-migraine triptan drugs are 5-HT(1B/1D) receptor agonists which are thought to block the neurotransmitter/neuropeptide release from sensory nerve terminals and directly constrict blood vessel smooth muscles. In the present study, we have investigated the anatomical basis for a possible modulation of glutamate release from trigeminal ganglion neurons by 5-HT(1B/1D) receptor agonists and by 5-HT1F receptor agonists, using double immunohistochemical staining technique in the rat. The majority… CONTINUE READING
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