Co-immobilization of multiple enzymes by metal coordinated nucleotide hydrogel nanofibers: improved stability and an enzyme cascade for glucose detection.

@article{Liang2016CoimmobilizationOM,
  title={Co-immobilization of multiple enzymes by metal coordinated nucleotide hydrogel nanofibers: improved stability and an enzyme cascade for glucose detection.},
  author={Hao Liang and Shuhui Jiang and Qipeng Yuan and Guangwei Li and Feng Y. Wang and Zijie Zhang and Juewen Liu},
  journal={Nanoscale},
  year={2016},
  volume={8 11},
  pages={
          6071-8
        }
}
Preserving enzyme activity and promoting synergistic activity via co-localization of multiple enzymes are key topics in bionanotechnology, materials science, and analytical chemistry. This study reports a facile method for co-immobilizing multiple enzymes in metal coordinated hydrogel nanofibers. Specifically, four types of protein enzymes, including glucose oxidase, Candida rugosa lipase, α-amylase, and horseradish peroxidase, were respectively encapsulated in a gel nanofiber made of Zn(2… CONTINUE READING

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