Co-expression of the voltage-gated potassium channel Kv1.4 with transient receptor potential channels (TRPV1 and TRPV2) and the cannabinoid receptor CB1 in rat dorsal root ganglion neurons

@article{Binzen2006CoexpressionOT,
  title={Co-expression of the voltage-gated potassium channel Kv1.4 with transient receptor potential channels (TRPV1 and TRPV2) and the cannabinoid receptor CB1 in rat dorsal root ganglion neurons},
  author={U. Binzen and W. Greffrath and S. Hennessy and M. Bausen and R. Treede},
  journal={Neuroscience},
  year={2006},
  volume={142},
  pages={527-539}
}
  • U. Binzen, W. Greffrath, +2 authors R. Treede
  • Published 2006
  • Medicine, Chemistry
  • Neuroscience
  • Potassium channels contribute to basic neuronal excitability and modulation. Here, we examined expression patterns of the voltage-gated potassium channel Kv1.4, the nociceptive transduction channels TRPV1 and TRPV2 as well as the putative anti-nociceptive cannabinoid receptor CB1 by immunofluorescence double-labelings in sections of rat dorsal root ganglia (DRGs). Kv1.4, TRPV1 and CB1 were each detected in about one third of neurons (35.7+/-0.5%, 29.4+/-1.1% and 36.4+/-0.5%, respectively, mean… CONTINUE READING

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