Co-expression of heparin-binding EGF-like growth factor and related peptides in human gastric carcinoma.

@article{Naef1996CoexpressionOH,
  title={Co-expression of heparin-binding EGF-like growth factor and related peptides in human gastric carcinoma.},
  author={Markus Naef and Mitsuhiro Yokoyama and Helmut Friess and Markus W. B{\"u}chler and Murray Korc},
  journal={International journal of cancer},
  year={1996},
  volume={66 3},
  pages={315-21}
}
Heparin-binding epidermal growth factor (EGF)-like growth factor (HB-EGF) is a member of the EGF family of polypeptide growth factors, which includes EGF, transforming growth factor alpha(TGF-alpha), amphiregulin (AR) and betacellulin (BTC). To assess the potential role of HB-EGF in human gastric carcinomas, the expression of HB-EGF and EGF receptor (EGF-R) was examined in normal and cancerous gastric tissues and cultured gastric cancer cell lines. By Northern blot analysis, there was a 4.7… CONTINUE READING

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