Co-expression of RON and MET is a prognostic indicator for patients with transitional-cell carcinoma of the bladder

@article{Cheng2005CoexpressionOR,
  title={Co-expression of RON and MET is a prognostic indicator for patients with transitional-cell carcinoma of the bladder},
  author={H-L Cheng and H Liu and Y Lin and Hong-zhang Chen and P-Y Hsu and T. Chang and Cheuk-Lam Ho and T-S Tzai and N-H Chow},
  journal={British Journal of Cancer},
  year={2005},
  volume={92},
  pages={1906 - 1914}
}
Recepteur d'Origine Nantais (RON) is a distinct receptor tyrosine kinase in the c-met proto-oncogene family. We examined the mutational and expression patterns of RON in eight human uroepithelial cell lines. Biological effects of RON overexpression on cancer cells were investigated in vitro, and the prognostic significance of RON and/or c-met protein (MET) expression was analysed in a bladder cancer cohort (n=183). There was no evidence of mutation in the kinase domain of RON. Overexpression of… CONTINUE READING

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The significance of macrophage stimulating protein (MSP)/RON signaling pathway in the progression of human bladder cancer

  • NH Chow, YJ Lin, +5 authors HS Liu
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  • 2003
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