Co-encapsulation of pancreatic islets and pentoxifylline in alginate-based microcapsules with enhanced immunosuppressive effects

@inproceedings{Azadi2016CoencapsulationOP,
  title={Co-encapsulation of pancreatic islets and pentoxifylline in alginate-based microcapsules with enhanced immunosuppressive effects},
  author={Seyedeh Azin Azadi and Ebrahim Vasheghani-Farahani and Sameereh Hashemi-Najafbabadi and Aliashraf Godini},
  booktitle={Progress in biomaterials},
  year={2016}
}
Alginate-based scaffolds have received considerable attention for biomedical application because of their biocompatibility and ease of preparation. The application of alginate hydrogels for encapsulation of pancreatic islets is known as a potential treatment for type I diabetes. In this study, dextran-spermine coated microcapsules of alginate containing pancreatic islets were prepared, and then co-cultured with lymphocytes for 7 days. In addition, to prevent fibrosis and evaluating the effect… CONTINUE READING
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