Co-electrospun dual scaffolding system with potential for muscle-tendon junction tissue engineering.

@article{Ladd2011CoelectrospunDS,
  title={Co-electrospun dual scaffolding system with potential for muscle-tendon junction tissue engineering.},
  author={Mitchell R Ladd and Sang Jin Lee and Joel D. Stitzel and Anthony J Atala and James J Yoo},
  journal={Biomaterials},
  year={2011},
  volume={32 6},
  pages={1549-59}
}
Tissue engineering has had successes developing single tissue types, but there is a need for methods that will allow development of composite tissues. For instance, muscle-tendon junctions (MTJ) require a seamless interface to allow force transfer from muscle to tendon. One challenge in engineering MTJs is designing a continuous scaffold suitable for both tissue types. We aimed to create a dual scaffold that exhibits regional mechanical property differences that mimic the trends seen in native… CONTINUE READING

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