Co-delivery of curcumin and serratiopeptidase in HeLa and MCF-7 cells through nanoparticles show improved anti-cancer activity.

@article{Jaiswal2018CodeliveryOC,
  title={Co-delivery of curcumin and serratiopeptidase in HeLa and MCF-7 cells through nanoparticles show improved anti-cancer activity.},
  author={S. Jaiswal and P. Mishra},
  journal={Materials science & engineering. C, Materials for biological applications},
  year={2018},
  volume={92},
  pages={
          673-684
        }
}
  • S. Jaiswal, P. Mishra
  • Published 2018
  • Materials Science, Medicine
  • Materials science & engineering. C, Materials for biological applications
  • Curcumin was employed to prepare anticancer nanoparticles (size 175 ± 15 nm) using anti-inflammatory enzyme serratiopeptidase by desolvation method. Here serratiopeptidase acted as a carrier as well as bioactive molecule in the nanoformulations. The Cur-SPD NPs (curcumin loaded serratiopeptidase nanoparticles) were characterized using DLS, FESEM and FTIR. The in vitro release behavior depicted biphasic pattern at 37 °C (pH 7.4) and release of 95% of both molecules occurred in 24 h… CONTINUE READING
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    References

    SHOWING 1-10 OF 75 REFERENCES
    Preparation and characterization of albumin nanoparticles encapsulating curcumin intended for the treatment of breast cancer
    • 95
    Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2.
    • 329
    • PDF
    Curcumin induces apoptosis in breast cancer cells and inhibits tumor growth in vitro and in vivo.
    • Zhidong Lv, X. Liu, +4 authors B. Kong
    • Biology, Medicine
    • International journal of clinical and experimental pathology
    • 2014
    • 93
    • PDF