Co-analysis of brain structure and function using fMRI and diffusion-weighted imaging.

@article{Phillips2012CoanalysisOB,
  title={Co-analysis of brain structure and function using fMRI and diffusion-weighted imaging.},
  author={Jeffrey S. Phillips and Adam S. Greenberg and John A. Pyles and Sudhir K. Pathak and Marlene Behrmann and Walter Schneider and Michael J. Tarr},
  journal={Journal of visualized experiments : JoVE},
  year={2012},
  volume={69}
}
The study of complex computational systems is facilitated by network maps, such as circuit diagrams. Such mapping is particularly informative when studying the brain, as the functional role that a brain area fulfills may be largely defined by its connections to other brain areas. In this report, we describe a novel, non-invasive approach for relating brain structure and function using magnetic resonance imaging (MRI). This approach, a combination of structural imaging of long-range fiber… 

Figures and Tables from this paper

Multimodal Imaging Brain Connectivity Analysis (MIBCA) toolbox
TLDR
The MIBCA toolbox is a fully automated all-in-one connectivity toolbox that offers pre-processing, connectivity and graph theoretical analyses of multimodal image data such as diffusion-weighted imaging, functional magnetic resonance imaging (fMRI) and positron emission tomography (PET).
Altered topology of neural circuits in congenital prosopagnosia
TLDR
These findings shed new light on the neural perturbations underlying CP, and the analytic approach adopted may have utility in elucidating the neural basis of other neurodevelopmental disorders such as dyslexia or amusia.
Verbal Fluency Is Affected by Altered Brain Lateralization in Adults Who Were Born Very Preterm
TLDR
The results show that verbal fluency is affected by altered functional lateralization in adults who were born very preterm.
Fluency Is Affected by Altered Brain Lateralization in Adults Who Were Born Very Preterm
TLDR
The results show that verbal fluency is affected by altered functional lateralization in adults who were born very preterm, and decreased brain activity suppression in the right sensorimotor cortex was associated with worse on-line performance on the hard letter trials.
Stimulus Dependent Dynamic Reorganization of the Human Face Processing Network
TLDR
It is suggested that the dynamic GLM network analysis approach, developed here for the face network, provides a general framework for modeling the dynamics of blocked stimulus-dependent connectivity experimental designs and hence can be applied to a host of neuroimaging studies.
Impairment of the face processing network in congenital prosopagnosia.
TLDR
A general framework is offered which, it is believed, best integrates the behavioral and neural findings, and offers a platform for generating hypotheses for future studies of congenital prosopagnosia.
Experience Shapes the Development of Neural Substrates of Face Processing in Human Ventral Temporal Cortex
TLDR
Functional magnetic resonance imaging in children and adults found a sequential development, in which the topology of face‐selective activations across the VTC was matured by age 7, but the spatial extent and degree of face selectivity continued to develop past age 7 into adulthood.
...
...

References

SHOWING 1-10 OF 55 REFERENCES
Statistical Parametric Mapping: The Analysis of Functional Brain Images
In an age where the amount of data collected from brain imaging is increasing constantly, it is of critical importance to analyse those data within an accepted framework to ensure proper integration
Mapping complex tissue architecture with diffusion spectrum magnetic resonance imaging
TLDR
Methods are presented to map complex fiber architectures in tissues by imaging the 3D spectra of tissue water diffusion with MR, showing correspondence between the orientational maxima of the diffusion spectrum and those of the fiber orientation density at each location.
Diffusion tensor imaging and beyond
TLDR
This article reviews the recent advances in diffusion tensor imaging and three-dimensional reconstruction technologies for white matter tracts since 2000, including more sophisticated nontensor models to describe diffusion properties and to extract finer anatomical information from each voxel.
Diffusion MRI: From Quantitative Measurement to In vivo Neuroanatomy: Second Edition
TLDR
The fundamental theory of diffusion imaging is covered, its most promising applications to basic and clinical neuroscience are discussed, and cutting-edge methodological developments that will shape the field in coming years are introduced.
Three‐dimensional tracking of axonal projections in the brain by magnetic resonance imaging
TLDR
It is shown that neuronal pathways in the rat brain can be probed in situ using high‐resolution three‐dimensional diffusion magnetic resonance imaging and a newly designed tracking approach.
High-definition fiber tractography of the human brain: neuroanatomical validation and neurosurgical applications.
TLDR
From a clinical perspective, HDFT provides accurate structural connectivity studies in patients with intracerebral lesions, allowing qualitative and quantitative white matter damage assessment, aiding in understanding lesional patterns of white matter structural injury, and facilitating innovative neurosurgical applications.
Bayesian analysis of neuroimaging data in FSL
...
...