Co-administration of silymarin elevates the therapeutic effect of praziquantel through modulation of specific antibody profiles, Th1/Th2/Tregs cytokines and down-regulation of fibrogenesis in mice with Mesocestoides vogae (Cestoda) infection.
@article{Hrkov2020CoadministrationOS, title={Co-administration of silymarin elevates the therapeutic effect of praziquantel through modulation of specific antibody profiles, Th1/Th2/Tregs cytokines and down-regulation of fibrogenesis in mice with Mesocestoides vogae (Cestoda) infection.}, author={Gabriela Hr{\vc}kov{\'a} and Ter{\'e}zia Ma{\vc}{\'a}k Kuba{\vs}kov{\'a} and Katar{\'i}na Reiterov{\'a} and David Biedermann}, journal={Experimental parasitology}, year={2020}, pages={ 107888 } }
3 Citations
Antiparasitic Effects of Selected Isoflavones on Flatworms
- BiologyHelminthologia
- 2021
This review suggests that examined flavonoids and their derivates are promising molecules for antiparasitic drug research, due to lack of toxicity, isoflavons could be used directly for therapy, or as adjuvant therapy for diseases caused by medically important cestodes and trematodes.
Serotonin Signalling in Flatworms: An Immunocytochemical Localisation of 5-HT7 Type of Serotonin Receptors in Opisthorchis felineus and Hymenolepis diminuta
- BiologyBiomolecules
- 2021
It is suggested that the muscular structures of flatworms are deeply supplied by 5-HT7-IR elements, which can mediate the serotonin action in the investigated species and is an important component of the flatworm motor control system.
A
single‐step
synthesis of 1,3,4,
6‐tetraaryl
‐5‐aryliminopiperazin‐2‐one
- ChemistryJournal of Heterocyclic Chemistry
- 2020
We report here novel reaction that we found unprecedented, up to our knowledge. In a single step, we obtained unusual result. After magnificent efforts we could deduce the structure. We confirmed the…
References
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This review critically surveys the literature published mainly within this millennium on the new and emerging applications of silybin (pure, chemically defined substance) and silymarin (flavonoid…
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- Medicine, Biology
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Silymarin is a well tolerated and effective antidote for use in hepatotoxicity produced by a number of toxins, including A. phalloides, ethanol and psychotropic drugs.