Clustering patterns of LOD scores for asthma-related phenotypes revealed by a genome-wide screen in 295 French EGEA families.

@article{Bouzigon2004ClusteringPO,
  title={Clustering patterns of LOD scores for asthma-related phenotypes revealed by a genome-wide screen in 295 French EGEA families.},
  author={Emmanuelle Bouzigon and M -H Dizier and Christine Kr{\"a}henb{\"u}hl and Arnaud Lemainque and Isabella Annesi-Maesano and Christine B{\'e}tard and Jean Bousquet and Denis Charpin and Fr{\'e}d{\'e}ric Gormand and Michel Guilloud-Bataille and Jocelyne Just and Nicole Le Moual and Jean Maccario and R{\'e}gis Matran and Françoise Neukirch and M -P Oryszczyn and Evelyne Paty and Isabelle Pin and Myriam Rosenberg-Bourgin and Daniel Vervloet and Francine Kauffmann and Mark Lathrop and Florence Demenais},
  journal={Human molecular genetics},
  year={2004},
  volume={13 24},
  pages={3103-13}
}
A genome-wide scan for asthma phenotypes was conducted in the whole sample of 295 EGEA families selected through at least one asthmatic subject. In addition to asthma, seven phenotypes involved in the main asthma physiopathological pathways were considered: SPT (positive skin prick test response to at least one of 11 allergens), SPTQ score being the number of positive skin test responses to 11 allergens, Phadiatop (positive specific IgE response to a mixture of allergens), total IgE levels… CONTINUE READING

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