Clustering of main orthologs for multiple genomes.

  title={Clustering of main orthologs for multiple genomes.},
  author={Zheng Fu and Tao Jiang},
  journal={Computational systems bioinformatics. Computational Systems Bioinformatics Conference},
The identification of orthologous genes shared by multiple genomes is critical for both functional and evolutionary studies in comparative genomics. While it is usually done by sequence similarity search and reconciled tree construction in practice, recently a new combinatorial approach and a high-throughput system MSOAR for ortholog identification between closely related genomes based on genome rearrangement and gene duplication have been proposed in (11). MSOAR assumes that orthologous genes… CONTINUE READING


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