Clustering of HCV coinfections on HIV phylogeny indicates domestic and sexual transmission of HCV.

  title={Clustering of HCV coinfections on HIV phylogeny indicates domestic and sexual transmission of HCV.},
  author={Roger D. Kouyos and Andri Rauch and J{\"u}rg B{\"o}ni and Sabine Yerly and Cyril A Shah and Vincent Aubert and Thomas Klimkait and Helen Kovari and Alexandra Calmy and Matthias Cavassini and Manuel Battegay and Pietro Vernazza and Enos Bernasconi and Bruno Ledergerber and Huldrych F. G{\"u}nthard},
  journal={International journal of epidemiology},
  volume={43 3},
BACKGROUND HCV coinfection remains a major cause of morbidity and mortality among HIV-infected individuals and its incidence has increased dramatically in HIV-infected men who have sex with men(MSM). METHODS Hepatitis C virus (HCV) coinfection in the Swiss HIV Cohort Study(SHCS) was studied by combining clinical data with HIV-1 pol-sequences from the SHCS Drug Resistance Database(DRDB). We inferred maximum-likelihood phylogenetic trees, determined Swiss HIV-transmission pairs as monophyletic… CONTINUE READING


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