Clustering and functional cooperation of Ng-CAM and axonin-1 in the substratum-contact area of growth cones.

@article{Stoeckli1996ClusteringAF,
  title={Clustering and functional cooperation of Ng-CAM and axonin-1 in the substratum-contact area of growth cones.},
  author={Esther T Stoeckli and Urs Ziegler and A J Bleiker and Peter Groscurth and Peter Sonderegger},
  journal={Developmental biology},
  year={1996},
  volume={177 1},
  pages={15-29}
}
Growth cones and neurites of chicken dorsal root ganglia neurons cultured on laminin, Ng-CAM, or axonin-1 exhibit substratum-dependent morphology and growth patterns which are accompanied by distinctive distributions of axonin-1 and Ng-CAM in the growth cone membrane. On either Ng-CAM or axonin-1 substratum, both Ng-CAM and axonin-1 were depleted from some areas of the apical growth cone membrane. In contrast, on laminin, both axonin-1 and Ng-CAM remained randomly distributed. Removal of axonin… CONTINUE READING
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