Clusterin synergizes with IL-2 for the expansion and IFN-γ production of natural killer cells.

@article{Sonn2010ClusterinSW,
  title={Clusterin synergizes with IL-2 for the expansion and IFN-γ production of natural killer cells.},
  author={Chung Hee Sonn and Young-Bin Yu and Young-Joo Hong and Y W Shim and Jeffrey A Bluestone and B I Min and Kyung-Mi Lee},
  journal={Journal of leukocyte biology},
  year={2010},
  volume={88 5},
  pages={955-63}
}
CLU is a secreted, multifunctional protein implicated in several immunologic and pathologic conditions. As the level of serum CLU was shown to be elevated during inflammatory responses, we questioned if CLU might interact with circulating lymphocytes leading to functional consequences. To assess this possibility directly, mouse splenocytes and purified NK… CONTINUE READING