Clusterin production in the obstructed rabbit kidney: correlations with loss of renal function.

@article{Schlegel1992ClusterinPI,
  title={Clusterin production in the obstructed rabbit kidney: correlations with loss of renal function.},
  author={Peter N. Schlegel and Glenn Matthews and Z Cichoń and W K Aulitzky and C. Yan Cheng and Chao Ling Chen and Luciano Saso and Marc Goldstein and Olli A. J{\"a}nne and Caroline Bardin},
  journal={Journal of the American Society of Nephrology : JASN},
  year={1992},
  volume={3 5},
  pages={1163-71}
}
Clusterin, a protein associated with cell death, has been suggested as a marker of renal injury. Correlation of clusterin gene expression with changes in renal function and quantitative measurement of clusterin protein levels after ureteral obstruction have not been previously reported. With unilateral ureteral obstruction in rabbits as the experimental model, the time course of alterations in renal function, clusterin mRNA accumulation, and concentrations of clusterin protein in serum, urine… CONTINUE READING
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