Clusterin/Apolipoprotein J immunoreactivity is associated with white matter damage in cerebral small vessel diseases

@inproceedings{Craggs2016ClusterinApolipoproteinJI,
  title={Clusterin/Apolipoprotein J immunoreactivity is associated with white matter damage in cerebral small vessel diseases},
  author={Lucinda Craggs and Julie Taylor and Janet Y. Slade and Aiqing Chen and Christian Hagel and Gregor Kuhlenbaeumer and Anne Borjesson-Hanson and Matti H Viitanen and Hannu O. Kalimo and Vincent Deramecourt and Arthur Ernest Oakley and Raj N Kalaria},
  booktitle={Neuropathology and applied neurobiology},
  year={2016}
}
AIM Brain clusterin is known to be associated with the amyloid-β deposits in Alzheimer's disease (AD). We assessed the distribution of clusterin immunoreactivity in cerebrovascular disorders, particularly focusing on white matter changes in small vessel diseases. METHODS Post-mortem brain tissues from the frontal or temporal lobes of a total of 70 subjects with various disorders including cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL… CONTINUE READING
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