Cluster-randomized trials: A closer look.

  title={Cluster-randomized trials: A closer look.},
  author={Andrew D. McRae and Monica Taljaard and Charles Weijer},
  journal={Clinical trials},
  volume={13 3},
BACKGROUND The cluster-randomized trial is the methodology of choice for evaluating interventions administered at the group level such as public health and healthcare quality improvement interventions. Because of unique features of this design, it can be difficult to apply standard research ethics guidelines to cluster-randomized trials. The Ottawa Statement on the Ethical Design and Conduct of Cluster-Randomized Trials provides researchers and research ethics committees with comprehensive… CONTINUE READING

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