Cluster of an erythromycin-resistant variant of the Spanish multiply resistant 23F clone ofStreptococcus pneumoniae in South Africa

@article{Klugman1994ClusterOA,
  title={Cluster of an erythromycin-resistant variant of the Spanish multiply resistant 23F clone ofStreptococcus pneumoniae in South Africa},
  author={Keith P. Klugman and Tracey J. Coffey and Andrew Smith and Avril D Wasas and Melanie F Meyers and Brian G. Spratt},
  journal={European Journal of Clinical Microbiology and Infectious Diseases},
  year={1994},
  volume={13},
  pages={171-174}
}
A multiply resistant serotype 23F pneumococcus was cultured from a 3-year-old child with otitis media and five carriers at the child's day-care centre in South Africa. Attempts to eradicate carriage with mupirocin failed. The strains were identical to the spanish clone of multiply resistant pneumococci by serotype, antimicrobial susceptibility pattern, restriction analysis of the penicillin-binding protein 1A, 2B and 2X genes and by multilocus enzyme electrophoresis. The data suggest that this… CONTINUE READING