Cluster headache and the hypocretin receptor 2 reconsidered: a genetic association study and meta-analysis.

@article{Weller2015ClusterHA,
  title={Cluster headache and the hypocretin receptor 2 reconsidered: a genetic association study and meta-analysis.},
  author={C. M. Kellett S. R. Weller and Leopoldine A. Wilbrink and Jeanine J. Houwing-Duistermaat and Stephany C Koelewijn and Lisanne S. Vijfhuizen and Joost Haan and Michel D. Ferrari and Gisela M. Terwindt and Arn M. J. M. van den Maagdenberg and Boukje de Vries},
  journal={Cephalalgia : an international journal of headache},
  year={2015},
  volume={35 9},
  pages={741-7}
}
BACKGROUND Cluster headache is a severe neurological disorder with a complex genetic background. A missense single nucleotide polymorphism (rs2653349; p.Ile308Val) in the HCRTR2 gene that encodes the hypocretin receptor 2 is the only genetic factor that is reported to be associated with cluster headache in different studies. However, as there are… CONTINUE READING