Cluster analysis of networks generated through homology: automatic identification of important protein communities involved in cancer metastasis

@article{Jonsson2005ClusterAO,
  title={Cluster analysis of networks generated through homology: automatic identification of important protein communities involved in cancer metastasis},
  author={Pall F. Jonsson and Tamara Cavanna and Daniel Zicha and Paul A. Bates},
  journal={BMC Bioinformatics},
  year={2005},
  volume={7},
  pages={2 - 2}
}
Protein-protein interactions have traditionally been studied on a small scale, using classical biochemical methods to investigate the proteins of interest. More recently large-scale methods, such as two-hybrid screens, have been utilised to survey extensive portions of genomes. Current high-throughput approaches have a relatively high rate of errors, whereas in-depth biochemical studies are too expensive and time-consuming to be practical for extensive studies. As a result, there are gaps in… CONTINUE READING
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